Scalable platform for cellular and biochemical screening of combinatorial small-molecule libraries in droplets
Mihajlo Todorovic, Laura West, Frederic D. Sigoillot, Gianluca Etienne, Asitha Adrian Abeywardane, Antonin V. Tutter, Tushar Apsunde, Douglas S. Auld, Andrew Brady, Seth Carbonneau, Lia Ecker, Jian Fang, Christophe Freslon, Jacob Hale, Hidetomo Imase, , Ken Yamada
The paper introduces a scalable platform for screening combinatorial small-molecule libraries in droplets, demonstrating its effectiveness in discovering chemical inducers of proximity and supporting machine learning-based drug design.
bioRxiv · Jun 15, 2026 · PreprintCell Biology