A brain-body feedback loop driving HPA-axis dysfunction in breast cancer
Adrian M. Gomez, Yue Wu, Chao Zhang, Leah Boyd, Tse-Luen Wee, Joseph Gewolb, Corina Amor, Lucas Cheadle, Jeremy C. Borniger
This study shows that breast cancer disrupts hypothalamic GC rhythms by altering PVNCRH neuron activity, and that targeting these neurons can reduce tumor progression.
bioRxiv · Sep 13, 2024 · PreprintNeuroscience