Small molecule activation of the tumor suppressor kinase LKB1
Lin Song, Dominique C. Mitchell, Jin Liu, Logan B. Leak, Rigney E. Turnham, LeeAnn Wang, Zheng Wang, Changliang He, Luo Ding, Marc Adler, Timothy Kellett, Aidan Keith, Yeonjoo C Hwang, Gary K.L. Chan, Robert L. G. Gottschalk, , John Dozier Gordan
This study develops small molecules that activate the tumor suppressor kinase LKB1 and shows their therapeutic benefits in cancer cell lines.
Cell chemical biology · Aug 1, 2026Peer-reviewedBiochemistry