Author

Leon Chalil

McMaster University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jennifer Howe· 2 shared Karun Kar SinghiD· 2 shared Stephen W. SchereriD· 2 shared Alain VerloèsiD· 1 shared Alexandria AfonsoiD· 1 shared Alina Piekna· 1 shared Anran Cheng· 1 shared Antonio VitobelloiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Jennifer Howe

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2 papers

Recent·Most cited

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney L. Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad O. Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye‐Eude, Alain Verloès, , Karun Kar Singh

This study identifies impaired OTUD7A-Ankyrin regulation as a mechanism underlying neuronal dysfunction in 15q13.3 microdeletion syndrome using mouse and human models.

Molecular Psychiatry · Jan 5, 2023Peer-reviewedNeuroscience

CNTN5-/+ or EHMT2-/+ iPSC-Derived Neurons from Individuals with Autism Develop Hyperactive Neuronal Networks

Éric Deneault, Muhammad Faheem, Sean H. White, Deivid C. Rodrigues, Song Sun, Wei Wei, Alina Piekna, Tadeo Thompson, Jennifer Howe, Leon Chalil, Vickie Kwan, Susan Walker, Peter Pasceri, Frederick P. Roth, Ryan K. C. Yuen, , Stephen W. Scherer

The paper models ASD-related variants in iPSC-derived neurons and finds hyperactive neuronal networks in CNTN5-/+ and EHMT2-/+ lines.

eLife · Feb 11, 2019Peer-reviewedNeuroscience