Author

Lin Du

Chinese Academy of SciencesPrimary ORCID profile (0009-0002-8986-9812 · 7 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Lin DuiD7 papers · University of Illinois Chicago

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:optimal transport· 1 Organism:plant (other)· 1

Frequent Co-Authors

Jingmin KangiD· 2 shared Bing Bao· 1 shared Bohan ZhangiD· 1 shared Chunxiao DuiD· 1 shared Fuyan LiuiD· 1 shared Ge LiiD· 1 shared Gencheng HaniD· 1 shared Hai‐Xi SuniD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPlant Biology

Jingmin KangORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MF-PENS: an efficient and versatile nuclear extraction method for plant single-cell sequencing

Lin Du, Qing Liu, Hongling Zhou, Mengyue Zhao, Fuyan Liu, Tong Cheng, Mengjiao Zhang, Hao Yu, Zhe Liang, Jingmin Kang

MF-PENS improves single-nucleus RNA sequencing in plants by efficiently isolating high-quality nuclei from diverse tissues, enhancing gene capture and cell type annotation.

bioRxiv · Mar 14, 2025 · PreprintPlant Biology

Tim-3 promotes viral infection by suppressing USP25-TRAF3-IRF7 signaling pathway

Lin Du, Jinjie Chen, Chunxiao Du, Junrui Chen, Zhaoxiang Wang, Bing Bao, L.V. Zhonglin, Xing Chen, Meng Liang, Lanying Wang, Shun Xie, Yuxiang Li, Zhiding Wang, Ge Li, Jun Zhang, Gencheng Han

This study shows Tim-3 suppresses antiviral immunity by inhibiting the USP25-TRAF3-IRF7 signaling pathway in myeloid cells during VSV encephalitis.

Cellular Immunology · Feb 8, 2025Peer-reviewedImmunology

Optimal Transport Method-Based Gene Filter (GF) Denoising Algorithm for Enhancing Spatially Resolved Transcriptomics Data

Lin Du, Jingmin Kang, Hai‐Xi Sun, Bohan Zhang

This study introduces a gene filter denoising algorithm using optimal transport to reduce noise in spatially resolved transcriptomics data, improving clustering and cell type annotation.

bioRxiv · Jul 1, 2023 · PreprintBioinformatics