Aggresomes protect mRNA under stress in Escherichia coli
Linsen Pei, Yujia Xian, Xiaodan Yan, Charley Schaefer, Aisha H. Syeda, Jamieson A. L. Howard, Wei Yan Zhang, Hebin Liao, Fan Bai, Mark C. Leake, Yingying Pu
The paper shows that aggresomes in E. coli store mRNA under stress, aiding rapid recovery by protecting mRNA from degradation and facilitating translation reactivation.
Nature Microbiology · Aug 19, 2025Peer-reviewedBiophysics