KIR3DL1 and Tox identify clonally expanded encephalitogenic neuron-specific CD8+ T cells in autoimmune encephalitis
Sylvain Perriot, Samuel Jones, Raphaël Genolet, Amandine Mathias, Helen A. Lindsay, Sara Bobisse, Giovanni Di Liberto, Mathieu Canales, Lise Queiroz, Christophe Sauvage, Ingrid Wagner, Larise Oberholster, Marie Gimenez, Diane Bégarie, Stjepana Kovac, , Renaud Du Pasquier
The paper identifies clonally expanded neuron-specific CD8+ T cells in anti-Ri AIE patients using an unbiased approach and shows they express KIR3DL1 and TOX.
Nature Communications · Sep 29, 2025Peer-reviewedImmunology