Induction of Sertoli cells from human fibroblasts by NR5A1 and GATA4
Jianlin Liang, Nan Wang, Jing He, Jian Du, Yahui Guo, Lin Li, Wenbo Wu, Longping Liu, Chencheng Yao, Zheng Li, Kehkooi Kee
This study reprograms human fibroblasts into Sertoli cells using NR5A1 and GATA4, showing they resemble primary Sertoli cells and support spermatogonia viability and immune suppression.
bioRxiv · Sep 29, 2018Developmental Biology