KDM6A Haploinsufficiency Is Insufficient to Disrupt Cochlear Structure and Auditory Function in Mouse Models of Kabuki Syndrome Type 2
Yuichi Shimizu, Shun Wakamori, Loryn Smith, Ghazaleh Behnammanesh, Yohei Honkura, Jun Suzuki, Jonathan E. Bird, Yukio Katori, Shinichi Someya
This study examines whether Kdm6a deficiency causes cochlear pathology or auditory dysfunction in mouse models of Kabuki syndrome type 2, finding no overt cochlear or auditory issues in viable models.
bioRxiv · Oct 12, 2026 · PreprintDevelopmental Biology