Dishevelled2 Condensates control Axon Initial Segment (AIS) assembly and function through MTCL1-Dependent microtubule recruitment.
Sophie Belmonte, Sonia Poirault‐Chassac, Juliette Villagomez, Charlotte Isch, Ana Dorrego-Rivas, Margot Donier, Émilie Chagny, Ellyn Renou, Louis Vacher, Nathalie Aubailly, Maïté Marie Moreau, Mélissa David, Magali Mondin, Mireille Montcouquiol, Matthieu Sainlos, , Jérôme Ezan
This study identifies Dvl2 as a novel component of the axon initial segment (AIS) and reveals its role in AIS assembly through MTCL1-dependent microtubule recruitment.
bioRxiv · Oct 15, 2026 · PreprintNeuroscience