A conformationally heterogeneous bending pivot enables bent-to-straight transition in the central helix of mycobacterial FtsZ
Anu Sodhi, Sneh Lata, Sapana Rani, Lucky Singh, Jagrity Choudhury, Barnali Neel Chaudhuri
This study uses multi-temperature crystallography and ensemble modeling to show that conformational heterogeneity in the bending pivot of mycobacterial FtsZ enables the bent-to-straight transition in its central helix.
bioRxiv · Oct 28, 2025 · PreprintBiophysics