Single-cell copy number calling and event history reconstruction
J. Kuipers, M. A. Tuncel, P. F. Ferreira, K. Jahn, N. Beerenwinkel
This paper develops SCICoNE, a statistical model for single-cell copy number analysis from low-depth sequencing data, showing its accuracy on simulated data and application to breast cancer samples.
bioRxiv · Apr 28, 2020Cancer Biology