Novel subthreshold retinal laser treatment with ERG-based thermal dosimetry activates hormetic heat response in pig RPE in vivo
M. Amirkavei, O. Kaikkonen, T. Turunen, A. Meller, J. Ahlgren, A. Kvanta, H. Andre, A. Koskelainen
This paper introduces a subthreshold retinal laser treatment using ERG-based thermal dosimetry to safely activate hormetic heat response in pig RPE, showing increased heat shock protein expression and autophagy without oxidative stress or apoptosis.
bioRxiv · Nov 29, 2022Bioengineering