BioengineeringbioRxiv
Novel subthreshold retinal laser treatment with ERG-based thermal dosimetry activates hormetic heat response in pig RPE in vivo
M. Amirkavei, O. Kaikkonen, T. Turunen…·A. Koskelainen
This paper introduces a subthreshold retinal laser treatment using ERG-based thermal dosimetry to safely activate hormetic heat response in pig RPE, showing increased heat shock protein expression and autophagy without oxidative stress or apoptosis.
DOI 10.1038/s41467-025-64095-6