Modification of DNA by a viral enzyme and charged tRNA
R. M. B. Silva, A. Slyvka, Y.-J. Lee, C. Guan, S. R. Lund, E. A. Raleigh, K. Skowronek, M. Bochtler, P. R. Weigele
The paper demonstrates how the phage Mu enzyme Mom uses charged tRNA to hypermodify adenine in DNA and reports the first in vitro reconstitution of this process.
bioRxiv · Mar 24, 2023Biochemistry