The Nse5/6-like SIMC1-SLF2 Complex Localizes SMC5/6 to Viral Replication Centers
M. Oravcova, M. Nie, N. Zilio, S. Maeda, Y. Jami-Alahmadi, E. Lazzerini-Denchi, J. A. Wohlschlegel, H. Ulrich, T. Otomo, M. Boddy
This paper identifies SIMC1 and SLF2 as novel subunits forming Nse5/6-like complexes that regulate SMC5/6 localization to viral replication centers and DNA damage sites.
bioRxiv · May 17, 2022Cell Biology