Author

T. Otomo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Otomo· 2 shared S. Maeda· 2 shared A. Leitner· 1 shared E. Lazzerini-Denchi· 1 shared G. C. Lander· 1 shared H. Ulrich· 1 shared J. A. Wohlschlegel· 1 shared K. Ohashi· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

C. Otomo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Nse5/6-like SIMC1-SLF2 Complex Localizes SMC5/6 to Viral Replication Centers

M. Oravcova, M. Nie, N. Zilio, S. Maeda, Y. Jami-Alahmadi, E. Lazzerini-Denchi, J. A. Wohlschlegel, H. Ulrich, T. Otomo, M. Boddy

This paper identifies SIMC1 and SLF2 as novel subunits forming Nse5/6-like complexes that regulate SMC5/6 localization to viral replication centers and DNA damage sites.

bioRxiv · May 17, 2022Cell Biology

The autophagic membrane tether ATG2A transfers lipids between membranes

S. Maeda, C. Otomo, T. Otomo

This study identifies ATG2A as a lipid-transfer protein that facilitates phagophore expansion by transferring lipids from the ER to the phagophore.

bioRxiv · Feb 20, 2019Cell Biology

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex

S. Chowdhury, C. Otomo, A. Leitner, K. Ohashi, R. Aebersold, G. C. Lander, T. Otomo

The paper characterizes the ATG2A-WIPI4 complex's role in autophagosome biogenesis through structural and biochemical analyses.

bioRxiv · Aug 9, 2018Biochemistry