Elucidation of an anaerobic pathway for metabolism of L-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteria
L. J. Rajakovich, B. Fu, M. Bollenbach, E. P. Balskus
This paper identifies an anaerobic pathway in gut bacteria that converts γ-butyrobetaine to trimethylamine, showing it is a major contributor to TMA production from L-carnitine in the human gut.
bioRxiv · Jan 25, 2021Biochemistry