Author

M. Brok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. DeMartino· 2 shared J. Drost· 2 shared L. S. Hiemcke-Jiwa· 2 shared M. J. A. Groot Koerkamp· 2 shared M. T. Meister· 2 shared T. de Souza· 2 shared A. Janse· 1 shared B. B. J. Tops· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

J. DeMartino

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2 papers

Recent·Most cited

Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma.

J. DeMartino, M. T. Meister, L. Visser, M. Brok, M. J. A. Groot Koerkamp, L. S. Hiemcke-Jiwa, T. de Souza, J. Merks, F. C. Holstege, T. Margaritis, J. Drost

This study uses single-cell transcriptomics to identify immune suppression and cell states in rhabdomyosarcoma that predict patient outcomes.

bioRxiv · Jul 15, 2022 · PreprintCancer Biology

Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

M. T. Meister, M. J. A. Groot Koerkamp, T. de Souza, W. B. Breunis, E. Frazer-Mendelewska, M. Brok, J. DeMartino, F. Manders, C. Calandrini, H. H. D. Kerstens, A. Janse, M. E. M. Dolman, S. Eising, K. P. S. Langenberg, M. van Tuil, , F. C. P. Holstege

This study generates tumor organoid models of rhabdomyosarcoma subtypes that closely resemble original tumors and can be used for drug screening and genetic modification.

bioRxiv · Jan 3, 2022Cancer Biology