Author

M. Bugiani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Grootemaat· 1 shared B. Schurink· 1 shared D. S. Metselaar· 1 shared E. E. Reits· 1 shared E. Hulleman· 1 shared E. R. Scholl· 1 shared E. Roos· 1 shared G. J. Kaspers· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Grootemaat

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in Atypical Teratoid/Rhabdoid Tumors

D. S. Metselaar, M. H. Meel, J. R. Goulding, P. Waranecki, M. C. de Gooijer, M. Breur, J. Koster, S. E. Veldhuijzen van Zanten, M. Bugiani, P. Wesseling, G. J. Kaspers, E. Hulleman

This study shows gemcitabine selectively kills ATRT by degrading SIRT1, activating p53 and SHH signaling, and significantly improves survival in xenograft models.

bioRxiv · Sep 2, 2023Cancer Biology

Lipid and nucleocapsid N-protein accumulation in COVID-19 patient lung and infected cells

A. Grootemaat, S. van der Niet, E. R. Scholl, E. Roos, B. Schurink, M. Bugiani, S. E. Miller, P. W. Larsen, J. Pankras, E. E. Reits, N. N. van der Wel

The paper examines the subcellular localization of SARS-CoV-2 proteins in lung tissue and infected cells, identifying lipid-filled compartments and the presence of viral proteins N and NSP4.

bioRxiv · Jun 24, 2021Microbiology