M1 and M2 macrophages differentially regulate colonic crypt renewal.
S. Raveenthiraraj, G. Awanis, M. Chieppa, A. Sobolewski
This study shows M1 macrophages, but not M2, increase colonic crypt proliferation and reduce goblet/tuft cell expression through contact-dependent crosstalk in a 3D co-culture model.
bioRxiv · Jul 13, 2022Cell Biology