RANK is an independent biomarker of poor prognosis in estrogen receptor-negative breast cancer and a therapeutic target in patient-derived xenografts
M. Ciscar, E. M. Trinidad, H. Perez-Montoyo, M. Alsaleem, M. J. Jimenez-Santos, M. Toss, A. Sanz-Moreno, A. Vethencourt, G. Perez-Chacon, A. Petit, M. T. Soler-Monso, J. Gomez-Miragaya, C. Gomez-Aleza, M. Jimenez, L. E. Dobrolecki, , E. Gonzalez-Suarez
This study shows RANK is a poor prognosis biomarker in ER-negative breast cancer and that targeting RANK improves outcomes in patient-derived xenografts.
bioRxiv · Dec 13, 2021 · PreprintCancer Biology