A. Petit

T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including Hepatocyte Growth factor

This study identifies an inflammatory microenvironment in T-ALL that supports progression, with HGF as a potential therapeutic target.

High CD44 expression identifies rare chemoresistant leukemic cells endowed with enhanced E-Selectin binding in T-ALL

The paper identifies a chemoresistant leukemic stem cell population in T-ALL with high CD44 expression and enhanced E-selectin binding, associated with poor prognosis and relapse.

RANK is an independent biomarker of poor prognosis in estrogen receptor-negative breast cancer and a therapeutic target in patient-derived xenografts

This study shows RANK is a poor prognosis biomarker in ER-negative breast cancer and that targeting RANK improves outcomes in patient-derived xenografts.

TWIST1 expression is associated with high-risk Neuroblastoma and promotes Primary and Metastatic Tumor Growth

This study shows TWIST1 promotes neuroblastoma growth and metastasis, and its suppression reduces tumor aggressiveness in mice.

Differentiation of human induced pluripotent stem cells into functional airway epithelium

This paper describes a method to differentiate human induced pluripotent stem cells into functional airway epithelium, achieving high cell purity and successful differentiation into multiple cell types.

Screening of clustered regulatory elements reveals functional cooperating dependencies in Leukemia.

The paper identifies co-regulated genes in leukemia using CRISPRi screening of super-enhancer regions, showing that combined inhibition of KIT and PDGFRA synergizes to impair leukemia cell growth.