Molecular mechanism for kinesin-1 direct membrane recognition
Z. Anton, J. F. Weijman, C. Williams, E. R. R. Moody, J. Mantell, Y. Y. Yip, J. A. Cross, T. A. Williams, R. A. Steiner, M. Crump, D. N. Woolfson, M. P. Dodding
This paper identifies a conserved amphipathic helix in kinesin-1 light chains that mediates direct membrane binding, challenging the previous understanding of lysosome positioning.
bioRxiv · Jan 20, 2021Cell Biology