M. Dagar

Pharmacological Evaluations of Select Herbal Extracts on TLR7/8-induced Cytokine and Chemokine Production in Macrophage-like Cells

This study evaluates the prophylactic effects of herbal extracts on TLR7/8-induced inflammation in macrophage-like cells, finding Withania somnifera most effective in reducing inflammatory gene expression.

Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells

This study shows that GPR56 activation by androgens enhances AR signaling through Rho and cAMP/PKA pathways, and its expression is higher in prostate tumors, suggesting it as a therapeutic target.