Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory
P. Tonnerre, D. Wolski, S. Subudhi, J. Al-Jabban, R. C. Hoogeveen, M. Damasio, H. K. Drescher, L. M. Bartsch, D. C. Tully, D. R. Sen, D. J. Bean, J. Brown, A. Torres-Cornejo, M. Robidoux, D. Kvistad, , G. M. Lauer
The paper shows that exhausted CD8 T cells do not fully recover functional memory after antigen removal in chronic HCV infection.
bioRxiv · Apr 3, 2021Immunology