Author

A. Cui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

N. Hacohen· 3 shared A. Aung· 1 shared A. Chudnovskiy· 1 shared A. P. Soleimany· 1 shared A. Torres-Cornejo· 1 shared A. Y. Kim· 1 shared B. K. Phillips· 1 shared C. A. Cottrell· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

N. Hacohen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PARG inhibition induces nuclear aggregation of PARylated PARP1

S. Paradkar, J. Purcell, A. Cui, S. Friedman, R. Sundaram, R. B. Jensen, R. S. Bindra

This study shows that PARG inhibition causes PARP1 to aggregate in the nucleus, leading to mis-localization and non-apoptotic cell death.

bioRxiv · Aug 12, 2023Cancer Biology

Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response

A. Chudnovskiy, T. B. Castro, S. Nakandakari-Higa, A. Cui, C.-H. Lin, M. Sade-Feldman, B. K. Phillips, J. Pae, L. Mesin, J. Bortolatto, L. D. Schweitzer, G. Pasqual, L.-F. Lu, N. Hacohen, G. D. Victora

The paper identifies dendritic cells that present antigens to CD4+ T cells in tumor-draining lymph nodes and the tumor microenvironment using LIPSTIC-based single-cell transcriptomics.

bioRxiv · Oct 25, 2022Immunology

Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

A. Aung, A. Cui, A. P. Soleimany, M. Bukenya, H. Lee, C. A. Cottrell, M. Silva, J. D. Kirkpatrick, P. Amlashi, T. K. Remba, S. Xiao, L. M. Froehle, W. Abraham, J. Adams, H. Suh, , J. R. Gregory

The paper shows that spatially restricted protease activity in lymph node follicles preserves antigen integrity, leading to stronger GC responses when antigens are targeted to follicular dendritic cells.

bioRxiv · Nov 15, 2021 · PreprintImmunology

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

P. Tonnerre, D. Wolski, S. Subudhi, J. Al-Jabban, R. C. Hoogeveen, M. Damasio, H. K. Drescher, L. M. Bartsch, D. C. Tully, D. R. Sen, D. J. Bean, J. Brown, A. Torres-Cornejo, M. Robidoux, D. Kvistad, , G. M. Lauer

The paper shows that exhausted CD8 T cells do not fully recover functional memory after antigen removal in chronic HCV infection.

bioRxiv · Apr 3, 2021Immunology