Lymphatic PD-L1 expression restricts tumor-specific CD8+ T cell responses
N. Cousin, S. Cap, M. Dihr, C. Tacconi, M. Detmar, L. Dieterich
This study shows that lymphatic PD-L1 limits tumor-specific CD8+ T cell responses by inducing apoptosis in central memory T cells, impacting tumor growth and immunotherapy efficacy.
bioRxiv · Oct 22, 2020Immunology