M. Dubach

Autocorrelation analysis of a phenotypic screen reveals hidden drug activity

The paper uses autocorrelation analysis on fluorescent images to detect drug activity affecting DNA damage response, finding higher compound activity for known DNA damage-related compounds.

Dimerization thermodynamics govern biological phase separation

This study proposes a dimer model to explain the thermodynamic mechanism of protein phase separation into biomolecular condensates, aggregates, and amyloids.