Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine.
K. M. Cowan, G. Macluskie, M. Finch, C. Palmer, J. Hair, M. Bylesjo, S. Lynagh, P. Brankin, M. McNeil, C. Low, D. Mallinson, E. Gourlay, H. Child, L. Cheyne, D. Bunton
The paper uses ex vivo lung organocultures and patient genomics to identify genetic predictors of drug response in COPD.
bioRxiv · May 27, 2019Pharmacology & Toxicology