Author

M. Genuth

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Organism:zebrafish· 1

Frequent Co-Authors

C. M. M. Crews· 1 shared E. An· 1 shared K. T. G. Samarasinghe· 1 shared L. Chu· 1 shared S. Holley· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

C. M. M. Crews

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1 paper

Recent·Most cited

OligoTRAFTACs: A Generalizable Method for Transcription Factor Degradation

K. T. G. Samarasinghe, E. An, M. Genuth, L. Chu, S. Holley, C. M. M. Crews

This paper introduces oligoTRAFTACs, a method to degrade transcription factors by combining DNA binding and E3 ligase recruitment, demonstrating efficacy in degrading c-Myc, brachyury, and in zebrafish models.

bioRxiv · Dec 20, 2021Cancer Biology