Hypoxic conditions promote a proliferative, poorly differentiated, and pro-secretory phenotype in COPD lung tissue progenitor cells in vitro
T. P. Dale, M. D. Santer, M. Haris, W. Zuo, N. R. Forsyth
This study shows hypoxia increases proliferation and secretory phenotype in COPD lung progenitor cells while reducing differentiation capacity.
bioRxiv · Mar 22, 2022Physiology