A Multi-omic and Multi-Species Analysis of Right Ventricular Failure
J. B. Mendelson, J. D. Sternbach, M. J. Doyle, L. Mills, L. M. Hartweck, W. Tollison, J. P. Carney, M. T. Lahti, R. W. Bianco, R. Kalra, F. Kazmirczak, C. Hindmarch, S. L. Archer, K. W. Prins, C. M. Martin
This study compares molecular pathways of right ventricular failure across pigs, rats, and humans using transcriptomics and proteomics, finding species-specific differences in fatty acid oxidation and electron transport chain regulation.
bioRxiv · Feb 8, 2023 · PreprintBiochemistry