Type I interferon alters invasive extravillous trophoblast function.
M. K. Simoni, S. G. Negatu, J. Y. Park, S. Mani, M. Arreguin, K. Amses, D. D. Huh, M. Mainigi, K. A. Jurado
This study shows that type I interferon reduces extravillous trophoblast invasion and induces a preeclampsia-like gene signature in an organ-on-a-chip model of implantation.
bioRxiv · Mar 11, 2024Immunology