M. Mainigi

Type I interferon alters invasive extravillous trophoblast function.

This study shows that type I interferon reduces extravillous trophoblast invasion and induces a preeclampsia-like gene signature in an organ-on-a-chip model of implantation.

Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19

This study shows that maternal extracellular vesicles from COVID-19 pregnancies alter trophoblast function, contributing to placental dysfunction.