Author

M. L. Jongsma

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Cell Biology· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Sienkiewicz· 1 shared D. J. van den Boomen· 1 shared D. M. van Elsland· 1 shared I. Berlin· 1 shared J. J. Neefjes· 1 shared J. P. Luzio· 1 shared P. J. Lehner· 1 shared

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2019-2019 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Sienkiewicz

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1 paper

Recent·Most cited

Cell BiologybioRxivNov 8, 2019

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

D. J. van den Boomen, A. Sienkiewicz, I. Berlin…·P. J. Lehner

The paper identifies C18orf8 as a core component of the Mon1-Ccz1 GEF for Rab7, showing its role in Rab7 activation, endosomal LDL trafficking, and NPC1-dependent lysosomal cholesterol export.

DOI 10.1038/s41467-020-19032-0

humanproteomics