Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers
R. Berhanu Lemma, T. Fleischer, E. Martinsen, M. Ledsaak, V. N. Kristensen, R. Eskeland, O. S. Gabrielsen, A. Mathelier
The paper identifies 13 transcription factors associated with DNA methylation modulation in cancer, showing their role in chromatin structure and transcription through emQTL analysis and experimental validation.
bioRxiv · May 10, 2021Cancer Biology