Author

A. Mathelier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

T. Fleischer· 3 shared V. N. Kristensen· 3 shared J. Ankill· 2 shared X. Tekpli· 2 shared A.-L. Borresen-Dale· 1 shared E. H. Kure· 1 shared E. Martinsen· 1 shared J. A. Castro-Mondragon· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

T. Fleischer

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3 papers

Recent·Most cited

Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation

J. Ankill, Z. Zhao, X. Tekpli, E. H. Kure, V. N. Kristensen, A. Mathelier, T. Fleischer

This study identifies common dysregulated transcriptional networks across cancers linked to loss of enhancer methylation through pan-cancer emQTL analysis.

bioRxiv · Sep 22, 2023Cancer Biology

Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

R. Berhanu Lemma, T. Fleischer, E. Martinsen, M. Ledsaak, V. N. Kristensen, R. Eskeland, O. S. Gabrielsen, A. Mathelier

The paper identifies 13 transcription factors associated with DNA methylation modulation in cancer, showing their role in chromatin structure and transcription through emQTL analysis and experimental validation.

bioRxiv · May 10, 2021Cancer Biology

Crosstalk between microRNA expression and DNA methylation drive the hormone-dependent phenotype of breast cancer

M. R. Aure, T. Fleischer, S. Bjorklund, J. Ankill, J. A. Castro-Mondragon, Oslo Breast Cancer Research Consortium (OSBREAC), A.-L. Borresen-Dale, K. K. Sahlberg, A. Mathelier, X. Tekpli, V. N. Kristensen

The paper investigates how microRNA expression and DNA methylation interact to drive hormone-dependent breast cancer phenotypes by analyzing two breast cancer cohorts.

Genome Medicine · Apr 29, 2021Peer-reviewedCancer Biology