Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent inhibitors.
L. E. de Vries, M. I. Sanchez, K. Groborz, L. Kuppens, M. Poreba, C. Lehmann, F. Yuan, S. Arastu-Kapur, M. Horn, M. Mares, M. Bogyo, M. Drag, E. Deu
The paper characterizes P. falciparum DPAP3 specificity and identifies structural factors causing differences in amino acid preferences between peptide substrates and covalent inhibitors.
bioRxiv · Aug 10, 2018 · PreprintBiochemistry