Author

K. Groborz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Drag· 3 shared W. Rut· 2 shared B. A. Martin· 1 shared B. Pawlik· 1 shared B. Turk· 1 shared E. Yoo· 1 shared G. S. Salvesen· 1 shared J. J. Yim· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

M. Drag

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Author profile →

3 papers

Recent·Most cited

Design of optical imaging probes by screening of diverse substrate libraries directly in disease tissue extracts

M. Tholen, J. J. Yim, K. Groborz, E. Yoo, B. A. Martin, N. S. van den Berg, M. Drag, M. Bogyo

The paper develops fluorescent probes for cancer detection by screening peptide libraries in tissue extracts, identifying highly effective tumor-specific probes that outperform previous designs.

bioRxiv · Jun 8, 2020Bioengineering

Substrate specificity profiling of SARS-CoV-2 main protease enables design of activity-based probes for patient-sample imaging

W. Rut, K. Groborz, L. Zhang, X. Sun, M. Zmudzinski, B. Pawlik, W. Mlynarski, R. Hilgenfeld, M. Drag

The paper profiles SARS-CoV-2 main protease substrate specificity to design activity-based probes for imaging Mpro in patient samples.

bioRxiv · Mar 7, 2020 · PreprintBiochemistry

The Activome: multiplexed probing of activity of proteolytic enzymes using mass cytometry-compatible activity-based probes (TOF-probes)

M. Poreba, K. Groborz, W. Rut, M. Pore, S. J. Snipas, M. Vizovisek, B. Turk, M. Drag, G. S. Salvesen

The paper develops lanthanide-labeled activity-based probes for mass cytometry to multiplex protease activity detection, demonstrating their use in identifying protease activomes in cell lines and blood cells.

bioRxiv · Sep 23, 2019Biochemistry