A pivotal role for Nrf2 in endothelial detachment- implications for endothelial erosion of stenotic plaques
S. Satta, M. McElroy, A. Langford-Smith, G. Ferris, J. E. Teasdale, Y. Kim, G. Niccoli, A. T. Tanjeko, J. Serre, G. G. Hazell, G. Sala Newby, P. Wang, J. L. Johnson, M. J. Humphries, G. Gayan-Ramirez, , S. J. White
This study shows that Nrf2 activation under elevated flow and smoking induces endothelial detachment, contributing to atherosclerotic plaque erosion and acute coronary syndromes.
bioRxiv · Feb 1, 2019Cell Biology