The panC-encoded pantothenate synthetase to tackle carbapenem-resistant OprD Pseudomonas aeruginosa mutant revealed through Tn-Seq
C. Van Maele, S. Caboche, M. Moutel, A. Bonnomet, S. Moussalih, E. Luczka, H. Jacquier, A. Muggeo, T. Guillard
This study identifies panC as a therapeutic target in OprD-deficient Pseudomonas aeruginosa by showing its role in growth and virulence through transposon sequencing and CRISPRi.
bioRxiv · Oct 19, 2023 · PreprintMicrobiology