AURKA destruction is decoupled from its activity at mitotic exit but suppresses interphase activity
A. Abdelbaki, H. B. Akman, M. Poteau, R. Grant, G. Guarguaglini, o. C. G. Gavet, C. Lindon
The paper investigates AURKA activity regulation, finding that its inactivation at mitotic exit depends on TPX2 degradation, not AURKA destruction, and that FZR1 suppresses interphase AURKA activity.
bioRxiv · Nov 21, 2019Cell Biology