M. Raatz

Infection dynamics in the urinary tract - The importance of non-planktonic phases during early infection and resistance evolution

This study uses a mathematical model to show that non-planktonic bacterial phases in UTIs increase infection risk and shape resistance evolution, with probiotic pretreatment improving antibiotic efficacy.

Provision of essential resources as a persistence strategy in food webs

This study shows that the provision of essential resources by a prey species can promote its persistence in food webs through higher-order interactions.

Understanding and leveraging phenotypic plasticity during metastasis formation

This study develops a mathematical model to understand how phenotypic plasticity influences metastasis formation and shows it can protect tumors from treatment, suggesting it as a therapeutic target.

Promoting extinction or minimizing growth? The impact of treatment on trait trajectories in evolving populations

This study examines how treatment affects trait evolution in populations by analyzing fitness landscapes and adaptation dynamics in birth and death rates.

The impact of phenotypic heterogeneity of tumour cells on treatment and relapse dynamics

This paper models how phenotypic heterogeneity in cancer cells affects treatment outcomes and relapse, showing that growth rate-dependent therapies delay relapse but may create resistant subpopulations.

Estimating parameters from multiple time series of population dynamics using Bayesian inference

This paper estimates model parameters and their variability from experimental time series data using Bayesian inference and dynamical population models, showing that cyclic dynamics provide more precise parameter estimates than steady states.

One man’s trash is another man’s treasure - the effect of bacteria on phytoplankton-zooplankton interactions in chemostat systems

This study shows that bacteria can significantly affect phytoplankton-zooplankton interactions in chemostat experiments under certain conditions, depending on experimental setup and predator traits.