The Therapeutic Antibody Profiler (TAP): Five Computational Developability Guidelines
M. Raybould, C. Marks, K. Krawczyk, B. Taddese, J. Nowak, A. P. Lewis, A. Bujotzek, J. Shi, C. M. Deane
The paper introduces TAP, a tool that identifies developability issues in therapeutic antibodies using five computational guidelines based on structural and charge properties.
bioRxiv · Jun 29, 2018Immunology