Determining the targeting specificity of the selective peroxisomal targeting factor Pex9
E. Yifrach, M. Ruowitz, L. D. Cruz Zaragoza, A. Tirosh, Z. Gazi, Y. Peleg, M. Kunze, M. Eisenstein, W. Schliebs, M. Schuldiner, R. Erdmann, E. Zalckvar
The paper investigates the targeting specificity of Pex9 by analyzing PTS1 motifs and structural features, finding that hydrophobicity of the amino acid before the PTS1 tripeptide determines its binding specificity.
bioRxiv · Feb 2, 2022Cell Biology