Implications of cholesterol and sphingomyelin in STING phosphorylation by TBK1
K. Takahashi, T. Niki, E. Ogawa, K. Fumika, Y. Nishioka, M. Sawa, H. Arai, K. Mukai, T. Taguchi
The paper shows that cholesterol and sphingomyelin are required for TBK1-mediated phosphorylation of STING at the TGN, mirroring in vivo conditions.
bioRxiv · Mar 15, 2021Cell Biology