The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia
E. Titus, F. Deiter, C. Shi, J. Wojciak, M. Scheinman, N. Jura, R. Deo
This paper reports the crystal structure of a cardiac calsequestrin filament and identifies mutations that disrupt filament formation, linking them to arrhythmia.
bioRxiv · Jul 31, 2019Biochemistry