Author

M. Seyffert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Fraefel· 3 shared C. Eichwald· 2 shared E. M. Schraner· 2 shared G. De Lorenzo· 2 shared G. Papa· 2 shared J. Vetter· 2 shared J.-L. Reymond· 2 shared K. Gunasekera· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

C. Fraefel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The interferon-γ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

S. O. Sutter, K. Tobler, M. Seyffert, A. Lkharrazi, J. Zöllig, E. M. Schraner, B. Vogt, H. Büning, C. Fraefel

The paper identifies IFI16 as a restriction factor for AAV2 transduction that acts independently of immune modulation by interfering with Sp1-dependent promoter activation.

bioRxiv · Jan 22, 2024 · PreprintMicrobiology

Rotavirus spike protein VP4 mediates viroplasm assembly by association to actin filaments

J. Vetter, G. Papa, M. Seyffert, K. Gunasekera, G. De Lorenzo, M. Wiesendanger, J.-L. Reymond, C. Fraefel, O. R. Burrone, C. Eichwald

This study shows that rotavirus VP4 interacts with actin filaments to facilitate viroplasm assembly, using a recombinant virus with a modified VP4 to demonstrate the role of this interaction.

bioRxiv · Jun 8, 2022Microbiology

A recombinant rotavirus harboring a spike protein with a heterologous peptide reveals a novel role of VP4 in viroplasm stability

G. Papa, J. Vetter, M. Seyffert, K. Gunasekera, G. De Lorenzo, M. Wiesendanger, E. M. Schraner, J.-L. Reymond, C. Fraefel, O. R. Burrone, C. Eichwald

This paper engineers a recombinant rotavirus with a VP4-BAP tag, showing VP4's role in viroplasm stability and replication fitness.

bioRxiv · May 13, 2021 · PreprintMicrobiology