Lipopolysaccharide-mediated resistance to host antimicrobial peptides and hemocyte-derived reactive-oxygen species are the major Providencia alcalifaciens virulence factors in Drosophila melanogaster
M. Shaka, A. Arias-Rojas, A. Hrdina, D. Frahm, I. Iatsenko
This study identifies lipopolysaccharide (LPS) and resistance to reactive oxygen species (ROS) as major virulence factors of P. alcalifaciens in Drosophila, revealing host-pathogen conflict mediated by these immune responses.
bioRxiv · May 17, 2022Microbiology